The crYOLO GUI is essentially a visualization of the command line interface. But don't worry, the command line interface is still available.

On left side of the GUI, you find all possible “Actions”:

• config: With this action you create the configuration file that you need to run crYOLO.
• train: This action lets you train crYOLO from scratch or refine an existing model.
• predict: If you have a (pre)trained model you can pick particles in your data set using this command.
• evaluation: This action helps you to quantify the quality of your model.

Each action has several parameters which are organized in tabs. Once you have chosen your settings you can press [Start], the command will be applied and crYOLO shows you the output:

An optimized filtering pipeline make the low-pass filter 2.5 times faster. Furthermore, it will now save downsized images to disk. This in consequence makes

• the training 75%
• picking 60% faster
• on-the-fly filtering is now 2.5 times faster compared to 1.4.0.