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You can use crYOLO either by command line or by using the GUI. The GUI should be easier for most users. You can start it with:

cryoloo.py

SCREENSHOT HERE

The crYOLO GUI is basically a visualization of the commandline interface. On left side, you find all possible “Actions”:

• conifg: With this action you create the configuration file that you need to run crYOLO.
• train: This action let you train crYOLO from scratch or refine an existing model.
• predict: If you have your model ready, you can pick the particles on your dataset using this command.
• evaluation: This action helps you need to quantify the “goodness” of your model.

Each action has several parameters which are organized in tabs. Once you chosen your settings you can press “Start”, the command will be applied and crYOLO shows you the output:

SCREENSHOT HERE

It will tell you when something went wrong. Pressing “edit” brings you back to your settings, where you can either edit the settings (in case something went wrong) or go to the next action.